Autobiographical Memory (AM) and Alzheimer’s Disease and Related Dementias (ADRD)
Conducted by: Sheridan Elder Research Centre
Contact: Research Assistant: Rebecca Hart, 905-845-9430, ext. 8616, rebecca.hart@sheridaninstitute.ca
Principle investigator: Professor Kate McLean, 905-569-4956, kmclean@utm.utoronto.ca
Length of Study: for at least two years beginning January 2007.
Purpose of Study: The study will investigate the extent to which the details and emotional quality of autobiographical memories in individuals with ADRD, (compared with older adults without dementia), change over time. The study will also examine whether the quality of autobiographical memories, and changes in these qualities over time influence the ability of the person with ADRD to use these memories as a social tool,
i.e. sharing stories to maintain important and intimate relationships in their life.

Pathways to Diagnosis: Cross-Cultural Experiences of the Pre-Diagnosis Period of Alzheimer’s Disease
Conducted by: New Women’s College Hospital (Dept. of Family & Community Medicine, University of Toronto) Research Group and
DementiaNET
Contact: Research Assistant: Kennedy Saldanha 416-323-6400 ext 4483, kennedy.Saldanha@wchospital.ca
Length of Study: for 6 months beginning July 2007.
Purpose of Study: The study is investigating the pre-diagnosis period of Alzheimer’s disease
with a view to understand the similarities and differences in beliefs and approaches across four Canadian cultural/linguistic groups.
In Toronto and the GTA, the focus is on the South Asian community.
Interviews will be approximately one hour in length.

Sirocco
Toronto Study Site: Toronto Memory Program
Contact: Laura Wilson 416-386-9761 laura@memorydisorders.ca
Length of Study: August 2007 to April 2008
Purpose of Study: Clinical testing of an investigational drug, AZD3480, to evaluate if it improves cognition in patients with mild or moderate AD compared to placebo (an inactive substance) and Donepezil.